DysportTM: BOTOX ® versus DysportTM:
There is now another, FDA-approved, wrinkle-reduction, prescription injection on the market in addition to BOTOX ®. The new injection is called DysportTM and was FDA approved in the USA in Spring 2009, although it has a history of use in other countries since 1991.
DysportTM and BOTOX ® are very similar compounds. They are both highly purified forms of Clostridum botulinum type A. During the purification process, the neurotoxin, botulinum, is combined with several proteins. In both cases, one of those proteins is human albumin, so anyone who is allergic to human albumin should not receive either medication. DysportTM is also combined with lactose, so anyone who is allergic to lactose should not receive DysportTM.
Due to different binding proteins used in the preparation, there is another important difference. DysportTM can disperse further in the muscles into which it is injected. Why is this important? Some clients have a hard time getting the effects they want with BOTOX ®. For example, men with very large foreheads need many injections and many units of BOTOX ®. Some women whose crows’ feet are very advanced also have a hard time getting enough BOTOX ® to get the effect they would like. In these cases, DysportTM may be a good alternative. With fewer injections, the neurotoxin will spread and create a more desirable effect throughout the muscle. There is, however, a downside due to this same effect. The increased dispersion of DysportTM also means there is an increased risk of side effects such as drooping eyebrows or eyelids. These are temporary and can sometimes be fixed with additional injections. However, sometimes, they cannot be fixed and a client has to wait several weeks or even months until the drooping wears off. This is also a risk with BOTOX ®, but is greater with DysportTM because of the increased dispersion of the product.
In most cases, the cost will be about the same for an individual client to have either product. The units are not interchangeable: for example, in the area in between the eyebrows, a standard dose for most women is 20 - 22 Units of BOTOX ® and 50 Units of DysportTM. The price per unit for BOTOX ® is 2-3 times higher than for DysportTM.
Dr Gambhir would be happy to discuss this further with you. Please make an appointment for a free consultation.